Making myelin water imaging “normal”: Robust acquisition for cervical cord with low peripheral nerve stimulation
Sharada Balaji1, Adam Dvorak1, Neale Wiley1, Laura Barlow2, Irene M. Vavasour3,4, Alex MacKay1,3, and Shannon H. Kolind1,3,4,5
1Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, 2MRI Research Centre, University of British Columbia, Vancouver, BC, Canada, 3Radiology, University of British Columbia, Vancouver, BC, Canada, 4International Collaboration on Repair Discoveries, Vancouver, BC, Canada, 5Medicine, University of British Columbia, Vancouver, BC, Canada
The standard myelin water imaging (MWI) sequence for cervical spinal cord, 3D gradient and spin echo (GRASE), was modified to allow scanning in “normal mode” (limiting imaging parameters that may cause physiologic stress) for patients who may not tolerate peripheral nerve stimulation or tissue heating due to MR-conditional implants or medical issues. Traditional 32-echo GRASE was replaced with 48-echo GRASE in normal mode. Myelin water fraction maps from the new sequence had better repeatability than the standard sequence. 48-echo GRASE is the recommended sequence for MWI in spinal cord, particularly for subjects who cannot be scanned outside of normal mode.
This abstract and the presentation materials are available to members only;
a login is required.