T1-weighted dynamic lung OE-MRI is challenging at 3 T using gradient echo acquisitions due to decreased T1 relaxivity of oxygen and substantial ∆R2* contribution. We implemented a dual echo T1-FFE-based method at 3 T and evaluated signal enhancement behaviour and ∆R2*. The proposed method is shown to produce negative contrast on oxygen enhancement signal due to dominance of ∆R2* at TE larger than 0.4 ms. We also demonstrated that the contrast property of the percentage signal enhancement (PSE) is TE dependent. Longer TE enables differentiation on PSE values between non-smokers and smokers.
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