Conventional brain DWI acquisitions are sensitive to physiological motion, which causes shot-to-shot phase variations between images. This makes accelerated, multi-shot imaging harder to achieve. We propose that motion compensated gradient waveforms will improve shot-to-shot phase stability. We found that both velocity and acceleration gradient moment nulling, particularly when diffusion encoding along the z-axis, improves shot-to-shot phase consistency at different cardiac trigger-delay times and reduces phase variation between repetitions for a fixed trigger-delay. We conclude that motion-compensated diffusion encoding gradients improve the phase stability between image shots.
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