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Abstract #1630

MR determination of the diffusion propagator: measurements on mouse spinal cord using a benchtop scanner

Alfredo Ordinola1, Walker Jackson2, and Evren Özarslan1
1Department of Biomedical Engineering, Linköping University, Linköping, Sweden, 2Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden


We demonstrate the experimental determination of the diffusion propagator, indicating a conditional probability density function with two spatial arguments. To this end, a recently introduced method was implemented on a benchtop MR scanner and incorporated into imaging sequences. The data involving two independent wavenumbers were transformed from the measurement domain to the spatial domain, yielding an apparent diffusion propagator. Experiments on freely diffusing water provides accurate determination of the diffusion propagator while apparent propagators measured in mouse spinal cord reveal significant differences between white and gray matter regions.

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