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Abstract #1773

Longitudinal resting-state functional connectivity changes with medication and nutrition treatment in chronic mild traumatic brain injury

Faezeh vedaei1, Mahdi Alizadeh1, George Zabrecky 1, Nancy Wintering 1, Anthony J. Bazzan 1, Daniel A. Monti 1, Andrew B. Newberg 1, and Feroze B. Mohamed 1
1Thomas Jefferson University, Philadelphia, PA, United States


This study provides comprehensive evaluation of functional rs-fMRI biomarkers that are associated with chronic mTBI symptoms and predicting treatment outcome and patient recovery. We evaluate the effect of medication and nutrition treatments on brain function and cognitive performance in chronic mTBI patients using resting-state fMRI metrics and neuropsychological test. We propose that treatment strategies compensate mTBI disrupt communication between brain network nodes. Our results help understanding the implication of treatment strategies in chronic mTBI patients and prediction of outcomes in brain function and cognitive recovery.

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