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Abstract #1775

DWI of cholesteatomas: An initial assessment based on RESOLVE and SPEN MRI

Martins Otikovs1, Debbie Anaby2, Shai Shrot2, Noam Nissan2, and Lucio Frydman1,3
1Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot, Israel, 2Sheba Medical Center, Ramat Gan, Israel, 3Azrieli National Center for Brain Imaging, Weizmann Institute of Science, Rehovot, Israel


Cholesteatomas are destructive lesions growing in the middle ear, in need of periodic assessments. Diffusion weighted imaging (DWI) at 3T provides clear contrast of these growths, facilitating their detection. However, the close presence of air-tissue interfaces within the ear channel results in geometric distortions that have led to adoption of non-EPI based methods for these high field evaluations. Herein we present results from initial DWI experiments performed for imaging cholesteatomas, which point out the value of Spatiotemporal Encoding (SPEN) DWI methods as promising alternatives to retrieve high-contrast, high-definition images.

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