Attenuation Correction in PET/MRI Pediatric Treated Brain Tumors: a Preliminary Comparison between the ZTE and Atlas Techniques
Paola Scifo1, Federico Fallanca1, Maurizio Barbera2, Annarita Savi1, Valentino Bettinardi1, Ilaria Neri1, Giovanna Gattuso3, Maura Massimino3, Paolo Verderio4, Sara Pizzamiglio4, Andrea Falini2,5, Luigi Gianolli1, Filippo Spreafico3, Maria Picchio1,5, and Cristina Baldoli2,5
1Nuclear Medicine, IRCCS San Raffaele Scientific Institute, Milan, Italy, 2Neuroradiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy, 3Department of Medical Oncology and Hematology, Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy, 4Unit of Bioinformatics and Biostatistics, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy, 5Vita-Salute San Raffaele University, Milan, Italy
A preliminary comparison between the two Atlas and ZTE attenuation correction methodologies in a group of pediatric patients with brain tumors is presented. The differences of the two ACmaps and PET images were calculated and the PET parameters were compared. Our results show that using ZTE or Atlas to generate ACmaps modifies the SUVs, but the differences in values are very small. Moreover, when metallic artefacts occur, both ZTE and Atlas show loss of signals but ACmapsAtlas has smaller artefacts.
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