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Abstract #1798

Dissolved-phase 129Xe longitudinal relaxation times at low and high magnetic field strengths

Nicholas Bryden1, Michele Kelley1, Christian T McHugh1, and Rosa T Branca1
1University of North Carolina Chapel Hill, Chapel Hill, NC, United States


We provide longitudinal relaxation measurements of hyperpolarized (HP) 129Xe gas dissolved in a variety of solvents at both low and high magnetic field strengths. The method of measuring T1 presented here is less sensitive than more commonly used methods to RF flip angle miscalibration, which has caused the significant variation in dissolved-phase 129Xe T1 values reported in the past. A field dependent study of gas depolarization by hollow membrane fibers commonly used to dissolve xenon in blood or other solvents is also included, which provides insight to experimental limitations on their use in both field regimes.

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