Abstract #1928

Structural Connectivity in Default Mode Network May Lateralize Temporal Lobe Epilepsy: A Graph-Theory Approach

Fatemeh Salimi ¹, Saeed Masoudnia ², Alireza Fallahi ^2,3, Narges Hoseini Tabatabaei⁴, Mohammadreza Ay^1,2, and Mohammad-Reza Nazem-Zadeh^1,2

¹Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Tehran, Iran (Islamic Republic of), ²Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran (Islamic Republic of), ³Biomedical Engineering, Hamedan University of Technology, Hamedan, Iran (Islamic Republic of), ⁴Medical School, Tehran University of Medical Sciences, Tehran, Iran (Islamic Republic of)

Synopsis

Difficulties in lateralizing the epileptogenic side of the brain challenge the temporal lobe epilepsy (TLE) surgery. We examined structural connectivity in default mode network (DMN) based on graph network analysis for specifying the epileptogenic side of the brain in TLE patients. The results showed significantly different connectivity in DMN nodes among the TLE patients compared to the control cohort. DMN regions with abnormal structural connectivity in TLE subjects corresponded with the epileptogenic brain sides.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.