Five neuroimaging markers including T1 volume, FLAIR signal intensity, and mean diffusivity in hippocampus, and fractional anisotropy in both posteroinferior cingulum and crus of fornix were used for lateralization of temporal lobe epilepsy (TLE). Support vector machine (SVM) was used as a classifier and for measuring the importance of neuroimaging attributes. The classification results demonstrated that the hippocampal volumetric and mean diffusivity showed the highest correct classification rate and the largest area under the curve (AUC) for the receiver operating characteristic (ROC), thus considered as the most important attributes of TLE laterality among all markers investigated in this study.
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