Epilepsy is a disease involving seizure initiation and often spread. sEEG has shown that areas of seizure spread are correlated with onset regions. We find that seed-to-voxel analysis via amplitude synchronization of fMRIs of epilepsy patients can also detect significant correlations between seizure onset and spread zones. These results validate fMRI analysis as a promising noninvasive method to detect other correlated brain regions that may be involved in seizure propagation.
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