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Abstract #2086

Whole Brain 1.3 mm isotropic APTw CEST at 3T in under 2 minutes

Patrick Liebig1, Maria Sedykh2, Kai Herz3,4, Yi-Cheng Hsu5, Moritz Fabian2, Angelika Mennecke2, Manuel Schmidt2, Arnd Doerfler2, and Moritz Zaiss2,3
1Siemens Healthcare GmbH, Erlangen, Germany, 2Department of Neuroradiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, 3Magnetic Resonance Center, Max-Planck-Institute for Biological Cybernetics, Tuebingen, Germany, 4Department of Biomedical Magnetic Resonance, University of Tübingen, Tuebingen, Germany, 5MR Collaboration, Siemens Healthineers Ltd., Shanghai, China

Synopsis

CEST MRI suffers from long acquisition times and/or limited volume coverage. Here we suggest using a spatio-temporal variable density Poisson disk design for whole brain APTw snapshot CEST. This enabled us to acquire 1.3 mm isotropic whole brain APTw CEST maps in under 2 minutes. All the reconstruction and necessary adjustment steps were implemented within the scanner software, enabling a push-button B0-corrected CEST measurement.

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