Abstract #2086

Whole Brain 1.3 mm isotropic APTw CEST at 3T in under 2 minutes

Patrick Liebig¹, Maria Sedykh², Kai Herz^3,4, Yi-Cheng Hsu⁵, Moritz Fabian², Angelika Mennecke², Manuel Schmidt², Arnd Doerfler², and Moritz Zaiss^2,3

¹Siemens Healthcare GmbH, Erlangen, Germany, ²Department of Neuroradiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, ³Magnetic Resonance Center, Max-Planck-Institute for Biological Cybernetics, Tuebingen, Germany, ⁴Department of Biomedical Magnetic Resonance, University of Tübingen, Tuebingen, Germany, ⁵MR Collaboration, Siemens Healthineers Ltd., Shanghai, China

Synopsis

CEST MRI suffers from long acquisition times and/or limited volume coverage. Here we suggest using a spatio-temporal variable density Poisson disk design for whole brain APTw snapshot CEST. This enabled us to acquire 1.3 mm isotropic whole brain APTw CEST maps in under 2 minutes. All the reconstruction and necessary adjustment steps were implemented within the scanner software, enabling a push-button B0-corrected CEST measurement.

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