Abstract #2167

Real-time automatic temperature regulation during MRI-guided Laser Interstitial Thermal Therapy (MR-LITT)

Manon Desclides^1,2,3, Valéry Ozenne^1,3,4,5, Pierre Bour², Guillaume Machinet⁶, Christophe Pierre⁶, Stéphane Chemouny², and Bruno Quesson^3,4,5

¹UMR5536 CRMSB, Université de Bordeaux, Bordeaux, France, ²Certis Therapeutics, Pessac, France, ³IHU Liryc, Electrophysiology and Heart Modeling Institute, Hopital Xavier Arnozan, Pessac, France, ⁴Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, University of Bordeaux, Bordeaux, France, ⁵INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, Bordeaux, France, ⁶ALPhANOV, Talence, France

Synopsis

We present here a method to automatically regulate heat deposition during Laser Interstitial Thermal Therapy to precisely control temperature evolution during the procedure. The method relies on real-time rapid volumetric thermometry using the Proton Resonance Frequency Shift technique and a regulation algorithm that adjusts every second the emitted power by the laser to force temperature to follow a predefined temperature-time profile.

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