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Abstract #2167

Real-time automatic temperature regulation during MRI-guided Laser Interstitial Thermal Therapy (MR-LITT)

Manon Desclides1,2,3, Valéry Ozenne1,3,4,5, Pierre Bour2, Guillaume Machinet6, Christophe Pierre6, Stéphane Chemouny2, and Bruno Quesson3,4,5
1UMR5536 CRMSB, Université de Bordeaux, Bordeaux, France, 2Certis Therapeutics, Pessac, France, 3IHU Liryc, Electrophysiology and Heart Modeling Institute, Hopital Xavier Arnozan, Pessac, France, 4Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, University of Bordeaux, Bordeaux, France, 5INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, Bordeaux, France, 6ALPhANOV, Talence, France


We present here a method to automatically regulate heat deposition during Laser Interstitial Thermal Therapy to precisely control temperature evolution during the procedure. The method relies on real-time rapid volumetric thermometry using the Proton Resonance Frequency Shift technique and a regulation algorithm that adjusts every second the emitted power by the laser to force temperature to follow a predefined temperature-time profile.

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