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Abstract #2168

Validation of a 3D MR temperature imaging sequence for use during breast magnetic resonance guided focused ultrasound treatments

Samuel Ian Adams1, Sara Johnson2, Henrik Odéen2, Dennis Parker2, and Allison Payne2
1Biomedical Engineering, University of Utah, Salt Lake City, UT, United States, 2Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States

Synopsis

This work presents a 3D MR temperature imaging (MRTI) sequence for breast MRgFUS. A 3D gradient echo with segmented echo planar imaging readout sequence with time-varying drift correction was used in female volunteers and tissue-mimicking phantoms. Temperature changes due to FUS heating in phantoms were measured with fiberoptic probes and compared to MRTI. Non-heating volunteer data was also acquired. Temperature in the phantom studies was accurate compared to FO probes with an RMSE of 1.0°C. Mean precision and accuracy of 1.05 and 1.29°C were measured in healthy volunteers. This sequence provides accurate and precise 3D temperature measurements for breast MRgFUS.

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