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Abstract #2238

Multiresolution MR elastography reconstruction and comparison of different direct inversion algorithms in the liver

Gwenaël Pagé1, Félicia Juléa1, Valérie Paradis2, Valérie Vilgrain1,3, Dominique Valla4, Bernard E. Van Beers1,3, and Philippe Garteiser1
1Laboratory of imaging biomarkers, INSERM UMR 1149, Paris, France, 2Center for research on inflammation, INSERM UMR 1149, Paris, France, 3Department of Radiology, University Hospital Paris Nord, Clichy, France, 4Hepatology service, University Hospital Paris Nord, Clichy, France


In this study we propose using a MR elastography reconstruction method adjust the ratio between wavelength and spatial resolution, by resampling the matrix of shear displacement locally, to optimize the quality of the reconstruction. This reconstruction algorithm was compared to existing direct inversion algorithms in phantoms, healthy volunteers and patients with liver fibrosis. We observed that the algorithm k-MDEV showing the best performance in phantoms and patients did not have the best repeatability. Our proposed method improved the diagnostic performance for advanced fibrosis, compared to classical direct inversion method, without a negative effect on repeatability.

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