Abstract #2241
Breathing task paradigm to improve the quality of pancreatic Magnetic Resonance Elastography
Nienke P.M. Wassenaar1, Anne-Sophie van Schelt1, Eric M. Schrauben1, Rémi van der Woude2, Jamila E. de Jong2, Jules L. Nelissen1, Hanneke W.M. van Laarhoven3, Jing Guo4, Ingolf Sack4, Jurgen H. Runge1, Aart J. Nederveen1, and Jaap Stoker1
1Radiology and Nuclear Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands, 2University of Twente, Enschede, Netherlands, 3Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands, 4Department of Radiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Synopsis
Free-breathing acquisition of pancreatic MR elastography can potentially introduce errors in stiffness reconstruction. In this study, breathing tasks are introduced during interleaved and reversed slice order MRE acquisition to determine if the quality of MRE increases. The shear-wave speed and octahedral shear strain signal-to-noise-ratio in the pancreas did not significantly change when using breathing tasks. However, the stability of the pancreas location over time increases when using breathing tasks combined with reversed slice ordering as well as the octahedral shear strain signal-to-noise-ratio in the whole abdomen. Future research should focus on comparing shear-wave speed reproducibility of both MRE methods.
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