MR Elastography of short T2 samples with Optimal Control-based RF pulses demonstrated on Achilles tendon
Pilar Sango-Solanas1, Kevin Tse-Ve-Koon1, Eric Van Reeth1,2, Cyrielle Caussy3,4, and Olivier Beuf1
1Univ Lyon, INSA-Lyon, Inserm, UCBL1, CNRS, CREATIS, UMR 5220, U1294, F-69621, Lyon, France, 2CPE Lyon, Département Sciences du Numérique, Lyon, France, 3Univ Lyon, CarMen Laboratory, INSERM, INRA, INSA Lyon, Université Claude Bernard Lyon 1,69495, Lyon, France, 4Hospices Civils de Lyon, Département Endocrinologie, Diabète et Nutrition, Hôpital Lyon Sud, 6949, Lyon, France
Magnetic Resonance Elastography (MRE) allows the quantitative characterization of mechanical properties of tissues based on the properties of shear wave propagation. MRE uses mostly oscillating motion encoding gradients (MEGs) to encode motion. Their presence involves long echo times, limiting the application of MEGs to very short T2 tissues. RF pulses designed with an optimal control (OC) algorithm applied with a constant gradient can simultaneously perform slice selection and motion encoding, enabling short echo times. In this study, we used OC pulses to mechanically quantify by MRI for the first time a very short T2 tissue such as the Achilles tendon.
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