Quantitative server-based analysis of MR elastography inversion methods on a phantom and the in vivo human kidney
Tom Meyer1, Stephan Rodrigo Marticorena Garcia1, Heiko Tzschätzsch1, Helge Herthum2, Mehrgan Shahryari1, Jürgen Braun2, Prateek Kalra3,4, Arunark Kolipaka3,4, and Ingolf Sack1
1Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, 2Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Berlin, Germany, 3Department of Biomedical Engineering, The Ohio State University, Columbus, OH, United States, 4Department of Radiology, The Ohio State University, Columbus, OH, United States
Magnetic resonance elastography (MRE) depicts the viscoelastic properties of soft tissues for diagnosis of various diseases such as tumors or fibrosis. However, different MRE inversion methods yield different results. This lack of comparability of different MRE inversion results hinders the dissemination of advanced reconstruction methods. Therefore, we here introduce an extensible, open-access web platform that offers multiple inversion techniques for multifrequency, three-dimensional MRE to promote comparison of values. We demonstrate the utility of the platform in phantom data and in vivo free-breathing multifrequency MRE data of the kidneys of healthy volunteers.
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