Alzheimer’s disease (AD) and other cognitive debilitating disease drive the need to improve neuro 7T MRI methods. We developed a multi-frequency magnetization transfer (MFMT) method for contrast improvement in 7T 3D MRI of the human hippocampus. MFMT applied to healthy volunteers demonstrated a 2.05 (p < 0.003) factor improvement in hippocampal contrast.
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