This study provides an assessment of the level of reproducibility of measurements of the magnetic susceptibility of the hippocampal sub-fields that can achieved at 7T in a group of healthy volunteers using high-resolution QSM in conjunction with ASHS segmentation. The 2 to 4 ppb range of the values of the average standard deviation of repeated measurements characterises the minimum level of susceptibility change that could be reliably assessed in longitudinal studies, such as those evaluating changes in the iron content of the hippocampal sub-fields in Alzheimer’s disease.
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