Alterations in 31P metabolite concentrations in the liver can be a consequence of liver disease and therefore 3D 31P MRSI can help in diagnosis and following progression and treatment response. However, commonly used 31P surface coils have a limited penetration depth and do not provide full coverage of the liver. We used an integrated 31P whole-body transmit coil with a local 31P receive array for 31P MRSI of the liver at a 7T MRI scanner. Here we demonstrate that 31P signals can be measured throughout the liver and 31P metabolite levels can be quantified with good to excellent test-retest reliability.
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