Meeting Banner
Abstract #2388

Assessment of resting-state networks in Alzheimer’s disease using combined spin- and gradient-echo fMRI

Elizabeth G. Keeling1,2, Maurizio Bergamino1, Nicholas J. Sisco1, Sudarshan Ragunathan1, C. Chad Quarles1, George P. Prigatano1, and Ashley M. Stokes1
1Barrow Neurological Institute, Phoenix, AZ, United States, 2Arizona State University, Tempe, AZ, United States


Functional connectivity, measured with BOLD-fMRI, has been previously used to study changes in aging and Alzheimer’s disease. A combined spin- and gradient-echo (SAGE) acquisition may be able to more sensitively distinguish between disease-related changes in functional connectivity. Therefore, this study aims to implement SAGE in resting-state fMRI to assess differences between macro- and microvasculature-sensitive data, between SAGE maps and single-echo methods, and between healthy aging and cognitively impaired cohorts’ functional networks.

This abstract and the presentation materials are available to members only; a login is required.

Join Here