The use of the endogenous molecule alpha-ketoglutarate (α-KG) as a non-persistent radical is examined to hyperpolarise 13C-glucose. A radical build-up curve was obtained and the maximum radical concentration was calculated to be 29 ± 3 mM. The microwave irradiation frequency was then examined to optimise the polarisation transfer between the electron on α-KG and glucose. A dissolution was successfully carried out and a hyperpolarised 13C spectrum of 13C-glucose was obtained.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords