Meeting Banner
Abstract #2458

The Larmor Frequency of a White Matter Magnetic Microstructure Model with Multiple Sources

Anders Dyhr Sandgaard1, Valerij G. Kiselev2, Noam Shemesh3, and Sune Nørhøj Jespersen1,4
1Department of Clinical Medicine, Center for Functionally Integrative Neuroscience, Aarhus University, Aarhus, Denmark, 2Medical Physics, Department of Radiology, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 3Champalimaud Research, Champalimaud Centre for the Unknown, Lisbon, Portugal, 4Department of Physics and Astronomy, Aarhus University, Aarhus, Denmark


Mapping tissue magnetic properties with MRI may improve the diagnosis of diseases and enhance our understanding of their basic mechanisms. However, MRI signals are sensitive to both structure and magnetic susceptibility, the so-called “magnetic microstructure”, rendering accurate susceptibility estimation a great challenge. Here, we present an analytical expression for the Larmor frequency of a white matter model of myelinated axons with axially symmetric microscopic susceptibility anisotropy and orientation dispersion. The modelled axons are surrounded by microscopic spherical inclusions with a scalar susceptibility. This goes beyond previous models of white matter magnetic microstructure.

This abstract and the presentation materials are available to members only; a login is required.

Join Here