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Abstract #2536

Reducing Artifacts in Readout-Segmented Spectroscopic Imaging at 7T

Amir Seginer1, Graeme A. Keith2, David A. Porter2, and Rita Schmidt3
1Siemens Healthcare Ltd, Rosh Ha'ayin, Israel, 2Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, Scotland, 3Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel


Readout-Segmented COKE (RS-COKE) is an Echo Planar Spectroscopic Imaging (EPSI) variant supporting larger spectral-widths and is therefore useful for spectral imaging at 7T. However, mismatches between the segments at the overlaps lead to artifacts, especially if the lipids signal is not suppressed (to avoid adversely affecting the metabolites signal). We developed a procedure to measure and reduce the readout segment mismatches – through signal and trajectory corrections – leading to improved spectral images and spectra. The procedure was tested by scanning both a special 3D head-shaped phantom – which includes a lipid layer – and human volunteers.

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