Abstract #2562
Non-invasive measures of resting perfusion and hemodynamic compromise in patients with large vessel steno-occlusive disease
Ece Su Sayin1, James Duffin1,2, Julien Poublanc3, David John Mikulis3, Joseph Arnold Fisher1,2, and Olivia Sobczyk2
1Department of Physiology, University of Toronto, Toronto, ON, Canada, 2Department of Anaesthesia and Pain Management, University Health Network, Toronto, ON, Canada, 3Joint Department of Medical Imaging and the Functional Neuroimaging Lab, University Health Network, Toronto, ON, Canada
Synopsis
Dynamic susceptibility contrast perfusion measures using hypoxia-induced deoxyhemoglobin (dOHb) and BOLD-MRI-CO2 CVR reveals that patients with steno-occlusive disease can have the degree of hymodynamic compromise classified into two severities by the differences in hemodynamic measures at rest and in response to stress.
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