Three-dimensional (3D) amide proton transfer (APT)-weighted (APTw) techniques have been applied in clinical work, However, image quality and feasibility of APTw imaging in normal kidneys at different scanning orientations have not been well confirmed. This study conducted on 27 healthy adult volunteers and all volunteers underwent intermittent end-respiratory breath-holding of axial and coronal 3D-APTw imaging. The preliminary results of this study show that the image quality of the image quality of renal APTw axial plane is better than that of coronal plane, and the reproducibility of APTw measurement values in axial plane is superior to that of coronal plane.
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