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Abstract #2707

Generalized Bloch model: a theory for pulsed magnetization transfer

Jakob Assländer1,2, Cem Gultekin3, Sebastian Flassbeck1,2, Steffen J Glaser4, and Daniel K Sodickson1,2
1Center for Biomedical Imaging, New York University School of Medicine, New York, NY, United States, 2Center for Advanced Imaging Innovation and Research, New York University School of Medicine, New York, NY, United States, 3Courant Institute of Mathematical Sciences, New York University, New York, NY, United States, 4Department of Chemistry, Technische Universität München, München, Germany

Synopsis

We introduce a classical model to describe magnetization transfer (MT). Like a quantum-mechanical description of spin dynamics and like the original Bloch equations, but unlike existing MT models, the proposed model is based on the algebra of angular momentum in the sense that it explicitly models the rotations induced by radio-frequency (RF) pulses. It unifies the original Bloch model, Henkelman's steady-state theory for magnetization transfer, and the commonly assumed rotation induced by hard, i.e. short, pulses, and describes experimental data better than previous models.

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