Abstract #2715

Free-breathing 3D CEST MRI of Human Liver at 3T Using MR Multitasking

Pei Han^1,2, Tianle Cao^1,2, Karandeep Cheema^1,2, Hsu-Lei Lee¹, Fei Han³, Nan Wang⁴, Hui Han¹, Yibin Xie¹, Anthony G. Christodoulou^1,2, and Debiao Li^1,2

¹Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ²Department of Bioengineering, UCLA, Los Angeles, CA, United States, ³Siemens Healthineers, Los Angeles, CA, United States, ⁴Department of Radiology, Stanford University, Stanford, CA, United States

Synopsis

We developed a 3D abdominal CEST MRI technique at 3T using MR Multitasking, which enables entire-liver coverage with free-breathing acquisition. By exploiting the correlation among images throughout the spatial, time, frequency offset, and respiration dimensions, the low-rank tensor framework shows the possibility to acquire the whole Z-spectrum of 53 frequency offsets within 11 min.

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