Free-breathing 3D CEST MRI of Human Liver at 3T Using MR Multitasking
Pei Han1,2, Tianle Cao1,2, Karandeep Cheema1,2, Hsu-Lei Lee1, Fei Han3, Nan Wang4, Hui Han1, Yibin Xie1, Anthony G. Christodoulou1,2, and Debiao Li1,2
1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2Department of Bioengineering, UCLA, Los Angeles, CA, United States, 3Siemens Healthineers, Los Angeles, CA, United States, 4Department of Radiology, Stanford University, Stanford, CA, United States
We developed a 3D abdominal CEST MRI technique at 3T using MR Multitasking, which enables entire-liver coverage with free-breathing acquisition. By exploiting the correlation among images throughout the spatial, time, frequency offset, and respiration dimensions, the low-rank tensor framework shows the possibility to acquire the whole Z-spectrum of 53 frequency offsets within 11 min.
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