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Abstract #2717

Fast WASAB1 post-processing for simultaneous B0 and B1 mapping for CEST imaging use in clinical routine

Christos Papageorgakis1, Eleni Firippi1, Benoit Gy1, Timothé Boutelier1, Ibrahim Khormi2,3,4, Oun Al-iedani2,3, Bryan Paton3,5, Jeannette Lechner-Scott 3,6,7, Amir Fazlollahi8, Anne-Louise Ponsonby9,10, Patrick Liebig11, Saadallah Ramadan2,3, Moritz Zaiss12, and Stefano Casagranda1
1Department of Research & Innovation, Olea Medical, La Ciotat, France, 2School of Health Sciences, College of Health, Medicine and Wellbeing,, University of Newcastle, Newcastle, Australia, 3Hunter Medical Research Institute, Newcastle, Australia, 4College of Applied Medical Sciences, University of Jeddah, Jeddah, Saudi Arabia, 5School of Psychology, College of Engineering, Science and Environment, University of Newcastle, Newcastle, Australia, 6Department of Neurology, John Hunter Hospital, New Lambton Heights, Australia, 7School of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, Australia, 8CSIRO Health and Biosecurity, Brisbane, Australia, 9The Florey Institute of Neuroscience and Mental Health, Victoria, Australia, 10Murdoch Children's Research Institute, Royal Children's Hospital, University of Melbourne, Victoria, Australia, 11Siemens Healthcare GmbH, Erlangen, Germany, 12Department of Neuroradiology, University Clinic Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany


This work provides a new method for fast post-processing of MRI data acquired using the WASAB1 sequence for simultaneous B0 and B1 mapping, used in CEST imaging for field inhomogeneity corrections. We are proposing a new processing method with outstanding acceleration of the parameter estimation procedure, without compromising the stability of the estimation. The stability of the method is demonstrated on phantom data and in vivo 3 Tesla clinical data.

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