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Abstract #2718

CEST MRI at 7T using an optimized parallel transmission saturation scheme

Thaddée Delebarre 1,2, Vincent Gras1,2, Franck Mauconduit1,2, Alexandre Vignaud1,2, Nicolas Boulant1,2, and Luisa Ciobanu1,2
1NeuroSpin, CEA, Saclay, France, 2Paris-Saclay University, Gif-sur-Yvette, France


Compared to the traditional circular polarization (CP) transmission mode, parallel transmission (pTx) excitation allows significant gains in contrast and homogeneity for Chemical Exchange Saturation Transfer (CEST) imaging. Using an in-house developed CEST-EPI sequence incorporating a pTx optimized CEST saturation block, we show that both tailored and universal pTx pulses provide significant improvement at 7T for APT-CEST, GluCEST and GlucoCEST imaging and enable saturation powers unattainable with CP.

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