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Abstract #2736

Brain morphometry abnormalities in children with Childhood Apraxia of Speech.

Paolo Bosco1, Laura Biagi1, Simona Fiori1, Clara Bombonato1, Michela Tosetti1, and Anna Chilosi1
1IRCCS Stella Maris Foundation, Pisa, Italy


Childhood Apraxia of Speech (CAS) is a pediatric speech sound disorder in which precision and consistency of speech movements are impaired in absence of neuromuscular and structural deficit. The cause of CAS remains poorly understood and few neuroimaging studies still exist in children with CAS. In this case-control study we compared both at ROI and voxel level the cerebral gray matter of CAS and healthy controls subjects. The statistical analyses show that gray matter in CAS children is increased in areas of motor circuitries subserving speech and in areas involving sensorimotor learning.

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