The potential value of whole-body MRI for the rheumatologist’s assessment and management of juvenile idiopathic arthritis patients
Varvara Choida1,2, Rachel Tattersall3,4, Jessica J Manson5, Debajit Sen1,5, Coziana Ciurtin1,5, and Margaret Hall-Craggs2,6
1Centre for Adolescent Rheumatology Versus Arthritis, University College London, London, United Kingdom, 2Centre for Medical Imaging, University College London, London, United Kingdom, 3Department of Rheumatology, Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom, 4Sheffield Children's NHS Foundation Trust, Sheffield, United Kingdom, 5Department of Rheumatology, University College London Hospitals NHS Foundation Trust, London, United Kingdom, 6Department of Radiology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
The impact of musculoskeletal inflammation detected by whole-body MRI (WBMRI) in adolescents with juvenile idiopathic arthritis (JIA) on rheumatologists’ clinical decisions was investigated. Anonymised clinical information collected for 30 patients before undergoing research WBMRI scans was examined by two rheumatologists who recorded independently their disease activity ratings, investigations, and treatment plans before and after reviewing the WBMRI reports. WBMRI findings changed rheumatologists’ disease activity ratings in half the patients and treatment plan in one-third, approximately. WBMRI detected inflammation in sites recommended for regional imaging pre WBMRI in less than half of cases and in other sites in more than one-half.
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