Abstract #2828

The potential value of whole-body MRI for the rheumatologist’s assessment and management of juvenile idiopathic arthritis patients

Varvara Choida^1,2, Rachel Tattersall^3,4, Jessica J Manson⁵, Debajit Sen^1,5, Coziana Ciurtin^1,5, and Margaret Hall-Craggs^2,6

¹Centre for Adolescent Rheumatology Versus Arthritis, University College London, London, United Kingdom, ²Centre for Medical Imaging, University College London, London, United Kingdom, ³Department of Rheumatology, Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom, ⁴Sheffield Children's NHS Foundation Trust, Sheffield, United Kingdom, ⁵Department of Rheumatology, University College London Hospitals NHS Foundation Trust, London, United Kingdom, ⁶Department of Radiology, University College London Hospitals NHS Foundation Trust, London, United Kingdom

Synopsis

The impact of musculoskeletal inflammation detected by whole-body MRI (WBMRI) in adolescents with juvenile idiopathic arthritis (JIA) on rheumatologists’ clinical decisions was investigated. Anonymised clinical information collected for 30 patients before undergoing research WBMRI scans was examined by two rheumatologists who recorded independently their disease activity ratings, investigations, and treatment plans before and after reviewing the WBMRI reports. WBMRI findings changed rheumatologists’ disease activity ratings in half the patients and treatment plan in one-third, approximately. WBMRI detected inflammation in sites recommended for regional imaging pre WBMRI in less than half of cases and in other sites in more than one-half.

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