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Abstract #2881

Mind the Myelin: Investigating the therapeutic impact of exercise on white matter damage in a rodent model of Fetal Alcohol Spectrum Disorders

Katrina Milbocker1, Eric Brengel1, Gillian LeBlanc1, and Anna Klintsova1
1Psychological & Brain Sciences, University of Delaware, NEWARK, DE, United States


Fetal Alcohol Spectrum Disorders (FASD) is an umbrella term used to identify individuals with a history of prenatal alcohol exposure which results in a spectrum of diagnostic disorders. 1 in 20 infants born in the U.S. has been diagnosed with an FASD, creating a major public health crisis. Deficits in corpus callosum myelination resulting from prenatal alcohol exposure have been correlated with impairments to perceptual learning and executive function in adolescents diagnosed with FASD. This study investigates the therapeutic potential of an exercise intervention to ameliorate alcohol-induced damage to corpus callosum myelination in a rodent model of FASD.

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