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Abstract #2919

Toward static-inhomogeneity-insensitive detection of neuro-electro-magnetic fields via compensated rotary saturation

Maximilian Gram1,2, Petra Albertova1,2, Verena Schirmer2, Martin Blaimer3, Matthias Gamer4, Martin J. Herrmann5, Peter Michael Jakob2, and Peter Nordbeck1,6
1Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany, 2Experimental Physics 5, University of Würzburg, Würzburg, Germany, 3Magnetic Resonance and X-ray Imaging Department Fraunhofer IIS, Fraunhofer Institute for Integrated Circuits IIS, Würzburg, Germany, 4Department of Psychology, University of Würzburg, Würzburg, Germany, 5Center of Mental Health, Dept. of Psychiatry, Psychosomatics, and Psychotherapy, University Hospital Würzburg, Würzburg, Germany, 6Comprehensive Heart Failure Center (CHFC), University Hospital Würzburg, Würzburg, Germany


Resonant absorption during spin-lock preparation can be used to measure tiny oscillating magnetic fields acting as direct evidence of electrical neuronal activity. Different spin-locking techniques were compared with respect to their sensitivity in magnetic field detection. As a specialty, the oscillating magnetic fields were generated by the built-in gradient system in an offcenter slice. The spin-lock time was identified as the crucial parameter for the performance of NEMO (neuro-electro-magnetic-oscillations) detection, since minima and maxima in the signal amplitude emerged in phantom and in vivo experiments. Affirmative, the experimental results show an excellent agreement with simulation results.

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