Abstract #2942

Alterations in ALPS index and choroid plexus volume after lumboperitoneal shunt in patients with idiopathic normal pressure hydrocephalus

Junko Kikuta¹, Koji Kamagata¹, Toshiaki Taoka², Kaito Takabayashi¹, Wataru Uchida¹, Akihiko Wada¹, Kaito Kawamura³, Chihiro Akiba⁴, Madoka Nakajima³, Masakazu Miyajima⁴, Shinji Naganawa⁵, and Shigeki Aoki¹

¹Department of Radiology, Juntendo University Graduate School of Medicine, Bunkyo-ku, Japan, ²Department of Innovative Biomedical Visualization, Graduate School of Medicine, Nagoya University, Nagoya, Japan, ³Department of Neurosurgery, Juntendo University Faculty of Medicine, Bunkyo-ku, Japan, ⁴Department of Neurosurgery, Juntendo Tokyo Koto Geriatric Medical Center, Koto-ku, Japan, ⁵Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Japan

Synopsis

Idiopathic normal pressure hydrocephalus (iNPH) is a condition resulting from impaired cerebrospinal fluid (CSF) absorption and excretion that is characterized by a triad of symptoms comprising cognitive decline, gait disturbance, and urinary incontinence. By improving CSF turnover through shunt surgery, symptoms of iNPH can become less severe. However, many mysterious points still exist in the mechanism of CSF dynamics in patients with iNPH. We examined alterations in ALPS index and choroid plexus volume after lumboperitoneal shunt (LPS) surgeries in patients with iNPH. Our results showed improvements in ALPS index and choroid plexus volume in these patients after LPS.

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