Alterations in ALPS index and choroid plexus volume after lumboperitoneal shunt in patients with idiopathic normal pressure hydrocephalus
Junko Kikuta1, Koji Kamagata1, Toshiaki Taoka2, Kaito Takabayashi1, Wataru Uchida1, Akihiko Wada1, Kaito Kawamura3, Chihiro Akiba4, Madoka Nakajima3, Masakazu Miyajima4, Shinji Naganawa5, and Shigeki Aoki1
1Department of Radiology, Juntendo University Graduate School of Medicine, Bunkyo-ku, Japan, 2Department of Innovative Biomedical Visualization, Graduate School of Medicine, Nagoya University, Nagoya, Japan, 3Department of Neurosurgery, Juntendo University Faculty of Medicine, Bunkyo-ku, Japan, 4Department of Neurosurgery, Juntendo Tokyo Koto Geriatric Medical Center, Koto-ku, Japan, 5Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Japan
Idiopathic normal pressure hydrocephalus (iNPH) is a condition resulting from impaired cerebrospinal fluid (CSF) absorption and excretion that is characterized by a triad of symptoms comprising cognitive decline, gait disturbance, and urinary incontinence. By improving CSF turnover through shunt surgery, symptoms of iNPH can become less severe. However, many mysterious points still exist in the mechanism of CSF dynamics in patients with iNPH. We examined alterations in ALPS index and choroid plexus volume after lumboperitoneal shunt (LPS) surgeries in patients with iNPH. Our results showed improvements in ALPS index and choroid plexus volume in these patients after LPS.
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