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Abstract #2961

Optimization of TE and Postprocessing for Nigrosome-1 Imaging using Wave-CAIPI Susceptibility Weighted Imaging at 3T

Caixia Fu1, Youmin Zhang2, Qing Li3, Wei Liu1, Naying He2, Yu Liu2, Daniel Polak4, E. Mark Haacke 5, and Fuhua Yan2
1MR Application Development, Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, 2Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, 3MR Collaborations, Siemens Healthineers Ltd., Shanghai, China, 4MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, 5Department of Radiology, Wayne State University, Detroit, MI, United States


In this work, Wave-CAIPI accelerated 3D SWI has been used to achieve whole brain imaging in about 3min 30s. Both short-TE and long-TE protocols were compared for the detection of the Nigrosome-1(N1) sign. The phase-mask formula and number of phase mask multiplications were adjusted to explorer their influence on the contrast-to-noise (CNR) of the N1 sign relative to adjacent tissues. The result showed that long-TE protocol had better CNR and made it easier to recognize the N1 sign. The adjusted phase-mask formula with an increased number of phase mask multiplications also helped to improve the CNR of the N1 sign.

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