Abstract #2961

Optimization of TE and Postprocessing for Nigrosome-1 Imaging using Wave-CAIPI Susceptibility Weighted Imaging at 3T

Caixia Fu¹, Youmin Zhang², Qing Li³, Wei Liu¹, Naying He², Yu Liu², Daniel Polak⁴, E. Mark Haacke ⁵, and Fuhua Yan²

¹MR Application Development, Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, ²Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, ³MR Collaborations, Siemens Healthineers Ltd., Shanghai, China, ⁴MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, ⁵Department of Radiology, Wayne State University, Detroit, MI, United States

Synopsis

In this work, Wave-CAIPI accelerated 3D SWI has been used to achieve whole brain imaging in about 3min 30s. Both short-TE and long-TE protocols were compared for the detection of the Nigrosome-1(N1) sign. The phase-mask formula and number of phase mask multiplications were adjusted to explorer their influence on the contrast-to-noise (CNR) of the N1 sign relative to adjacent tissues. The result showed that long-TE protocol had better CNR and made it easier to recognize the N1 sign. The adjusted phase-mask formula with an increased number of phase mask multiplications also helped to improve the CNR of the N1 sign.

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