Abstract #2967

White matter microstructure alterations using Generalized Q-Sampling Imaging in Moderate and Severe Obstructive Sleep Apnea

Peng Wang¹, Xinchun Li¹, Qi Wan¹, Wenjin Zou², Yihao Guo³, Mengzhu Wang⁴, Jianfeng Hu¹, Yu Peng¹, Xiaoying Xia¹, Xiaobin Xie¹, and Jieqiong Liu¹

¹Department of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China, ²The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), Guangzhou, China, ³MR Collaboration, Siemens Healthineers Ltd., Guangzhou, China, ⁴MR Scientific Marketing, Siemens Healthineers, Guangzhou, China

Synopsis

In the current study, we assessed possible alterations of brain white matter (WM) microstructure in patients with obstructive sleep apnea (OSA) using generalized q-sampling imaging (GQI). We found higher normalized quantitative anisotropy values of the bilateral superior longitudinal fasciculus, uncinate fasciculus, fornix, and corpus callosum bundle in the OSA group vs controls, which were related to multiple clinical indices of OSA.

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