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Abstract #2970

Structure-function relationships in the human hippocampus: new insights using track-weighted dynamic functional connectivity

Marshall A Dalton1, Jinglei Lv1, Arkiev D'Souza1, and Fernando Calamante1
1The University of Sydney, Sydney, Australia


The hippocampus is a brain structure central to a broad range of cognitive functions including episodic memory. In recent years, we have developed a greater understanding of the structural and functional connectivity of the human hippocampus. Despite these advances, we lack a detailed understanding of structure-function relationships of cortico-hippocampal connectivity. We addressed this gap by combining high-quality data from the Human Connectome Project with cutting-edge fibre-tracking and track-weighted dynamic functional connectivity methods to quantitatively characterise the relationship between anatomical and functional connectivity of the human hippocampus. Our results contribute to ongoing efforts to characterise structure-function relationships of the hippocampus.

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