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Abstract #2987

Use of Arterial Blood Contrast (ABC) to detect resting state networks at short TE

Fatemeh Taheriyan1, Zahrah Fazal1, Kevin Klein Gunnewiek1, Jenni Schulz1, Jose Marques1, and David G Norris1
1Radboud University, Donders Institute, Nijmegen, Netherlands


Arterial blood contrast increase the cerebral blood volume contribution to brain activation studies by suppressing grey matter signal using on-resonance magnetisation transfer. An increase in CBV will lead to an increase in signal, which is then complementary to BOLD. We performed multi-echo resting state fMRI in a group of 16 subjects and compared the results at TE=28ms with MT-off (standard BOLD) and TE=6.9 MT-on (ABC). Z-scores were higher for standard BOLD at all TEs but with higher variance in the z-score value. Dual regression results never the less showed high similarity activation maps for standard resting state networks.

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