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Abstract #3007

Clinical Value of Synthetic MRI and DWI in the diagnosis of Hippocampal Sclerosis in medial temporal lobe Epilepsy

Yucai Bai1, Jian LI1, Xiaocheng Wei2, Yaoxing Ma1, and Bing Chen1
1General Hospital of Ningxia Medical University, Ningxia yinchuan, China, 2GE Healthcare, Beijing, China


The purpose of this study is to explore the value of different quantitative parameters derived from Synthetic MRI and combined with DWI in the diagnosis of hippocampal sclerosis. It was concluded that the values of T1, T2 and ADC in the hippocampal sclerosis were significantly higher than those in the normal control group .In addition, the AUC of the combined model of T2 and ADC was 0.96, which was higher than that of ADC (AUC 0.884) or T2 alone (AUC 0.952). Its sensitivity, specificity, positive predictive value and negative predictive value were 0.95,0.91,0.81,0.98 respectively.

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