Radiomics has been increasingly used as potential quantitative imaging biomarkers for head and neck cancer diagnosis and treatment. However, the test-retest repeatability of radiomics features in the head and neck (HN) region is rarely investigated. This study aims to investigate the test-retest repeatability of MRI radiomics features in HN. Radiomics features were extracted from 15 volunteers receiving 4 re-positioned MRI scans with thermoplastic mask immobilization and flexible coils using 3D-T1w-TSE and 3D-T2w-TSE. The results found that test-retest repeatability of MRI radiomics features varied dependent on tissues and pulse sequences. Only a small percentage of radiomics features showed excellent test-retest repeatability.
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