Abstract #3012

Test-retest repeatability of MRI radiomics features in head and neck region using 3D-T1w-TSE and 3D-T2w-TSE: a prospective multi-scan study

Cindy xue^1,2, Jing Yuan¹, Yihang Zhou¹, Oilei Wong¹, Kin Yin Cheung³, and Siu Ki Yu³

¹Research Department, Hong Kong Sanatorium and Hospital, Hong Kong, Hong Kong, ²Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Hong Kong, Hong Kong, ³Medical Physics Department, Hong Kong Sanatorium and Hospital, Hong Kong, Hong Kong

Synopsis

Radiomics has been increasingly used as potential quantitative imaging biomarkers for head and neck cancer diagnosis and treatment. However, the test-retest repeatability of radiomics features in the head and neck (HN) region is rarely investigated. This study aims to investigate the test-retest repeatability of MRI radiomics features in HN. Radiomics features were extracted from 15 volunteers receiving 4 re-positioned MRI scans with thermoplastic mask immobilization and flexible coils using 3D-T1w-TSE and 3D-T2w-TSE. The results found that test-retest repeatability of MRI radiomics features varied dependent on tissues and pulse sequences. Only a small percentage of radiomics features showed excellent test-retest repeatability.

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