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Abstract #3032

Malignancy-specific structural-functional dyscoupling in brains with glioma

Siqi Cai1,2, Chunxiang Jiang1,2, Zhifeng Shi3, Shihui Zhou1,2, and Lijuan Zhang*1
1Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, 2University of Chinese Academy of Sciences, Beijing, China, 3Huashan Hospital of Fudan University, Shanghai, China


The structural-functional coupling in the connectivity of the contralesional hemisphere was enhanced and specific to the malignancy grades of glioma. Structural and functional networks in brains with low grade glioma featured with increased global and local efficiency, whereas the plasticity of the functional networks was limited in brians with high grade glioma. These findings provide new knowledge toward innovating the characterization of glioma.

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