Meeting Banner
Abstract #3033

Abnormal functional stability in patients with minimal hepatic encephalopathy.

LiMin Cai1 and HuaJun Chen1
1Fujian Medical University Union Hospital, Fuzhou, China


We investigated the stability of brain functional architectures and its relationship with cognitive impairment in cirrhotic patients. From healthy controls, to NHE, and to minimal hepatic encephalopathy(MHE) group, a stepwise reduction of FS was found in right supramarginal gyrus , right middle cingulate cortex, left superior frontal gyrus, and BPCC; whereas, a progressive increment of FS was observed in left middle occipital gyrus and right temporal pole. Mean FS was correlated with Psychometric Hepatic Encephalopathy Score among cirrhotic patients. FS index showed moderate discrimination potential between NHE and MHE. FS alteration could be potential biomarkers serving for diagnosis about MHE.

This abstract and the presentation materials are available to members only; a login is required.

Join Here