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Abstract #3036

Altered spontaneous brain activity in patients with comitant exotropia before and after surgery: a resting-state fMRI study

Qian Wu1, Hao Hu1, Wen Chen1, Lu Chen1, Jiang Zhou1, Xiaoquan Xu1, and Feiyun Wu1
1Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China


We investigate the brain functional alterations in patients with comitant exotropia (CE) before and after surgery, using resting-state functional magnetic resonance imaging with amplitude of low-frequency fluctuation. Our study suggested that CE may lead to decreased brain functional activities in visual-associated areas and the brain function could partially restore along with recovery of exodeviation after strabismus surgery. Besides, our results provided an explanation to the postoperative remnant of stereopsis impairment, which would be helpful to improve the clinical interventions for patients with CE.

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