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Abstract #3067

Relaxometry of the Substantia Nigra Pars Compacta and Subsegment Analysis: A Healthy Volunteer Study

Yasuhiro Fujiwara1, Shota Ishida2, Yuki Matta3, Masayuki Kanamoto3, and Hirohiko Kimura4
1Department of Life Sciences, Fuculty of Medical Image Sciences, Kumamoto University, Kumamoto, Japan, 2Department of Radiological Technology, Faculty of Medical Sciences, Kyoto College of Medical Science, Kyoto, Japan, 3Radiological Center, University of Fukui Hospital, Fukui, Japan, 4Department of Radiology, University of Fukui, Fukui, Japan


An anatomical atlas of the three regions (medial, dorsal, and ventrolateral) of the substantia nigra pars compacta (SNpc) were created based on neuromelanin (NM)-sensitive images, and Proton density, T1, and T2 values for each region were characterized in healthy volunteers. The T1 value of the ventrolateral group was higher than the other SNpc regions, which may be correlated with the NM concentration. The measured relaxation times can be used as baseline values for the SNpc.

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