Abstract #3067

Relaxometry of the Substantia Nigra Pars Compacta and Subsegment Analysis: A Healthy Volunteer Study

Yasuhiro Fujiwara¹, Shota Ishida², Yuki Matta³, Masayuki Kanamoto³, and Hirohiko Kimura⁴

¹Department of Life Sciences, Fuculty of Medical Image Sciences, Kumamoto University, Kumamoto, Japan, ²Department of Radiological Technology, Faculty of Medical Sciences, Kyoto College of Medical Science, Kyoto, Japan, ³Radiological Center, University of Fukui Hospital, Fukui, Japan, ⁴Department of Radiology, University of Fukui, Fukui, Japan

Synopsis

An anatomical atlas of the three regions (medial, dorsal, and ventrolateral) of the substantia nigra pars compacta (SNpc) were created based on neuromelanin (NM)-sensitive images, and Proton density, T1, and T2 values for each region were characterized in healthy volunteers. The T1 value of the ventrolateral group was higher than the other SNpc regions, which may be correlated with the NM concentration. The measured relaxation times can be used as baseline values for the SNpc.

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