Comparison of different T2 fitting models in renal tissue relaxometry
Wan-Ting Zhao1,2,3, Karl-Heinz Herrmann1, Martin Krämer1, Daniel Güllmar1, Jürgen R. Reichenbach1, and Verena Hoerr1,4,5
1Institute of Diagnostic and Interventional Radiology, University Hospital Jena, Jena, Germany, 2Center for Sepsis Control and Care, University Hospital Jena, Jena, Germany, 3Institute of Medical Microbiology, University Hospital Jena, Jena, Germany, 4Clinic for Radiology, University Hospital Muenster, Muenster, Germany, 5Heart Center, University Hospital Bonn, Bonn, Germany
While relaxation rate estimation substantially varies on the chosen fitting method, a tissue-specific T2 fitting scheme for the kidney is lacking. The current study aims to compare multiple T2 fitting methods, including square signal and mono-exponential with constant offsets, in high SNR and low SNR scenarios from identical data points. We compare standard deviations for fitting robustness and RMSE for the goodness of fit. Our finding suggests a mono-exponential with constant offsets is the most suitable method, for it yielded the lowest RMSE both in high and low SNR.
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