Abstract #3275

Comparison of different T2 fitting models in renal tissue relaxometry

Wan-Ting Zhao^1,2,3, Karl-Heinz Herrmann¹, Martin Krämer¹, Daniel Güllmar¹, Jürgen R. Reichenbach¹, and Verena Hoerr^1,4,5

¹Institute of Diagnostic and Interventional Radiology, University Hospital Jena, Jena, Germany, ²Center for Sepsis Control and Care, University Hospital Jena, Jena, Germany, ³Institute of Medical Microbiology, University Hospital Jena, Jena, Germany, ⁴Clinic for Radiology, University Hospital Muenster, Muenster, Germany, ⁵Heart Center, University Hospital Bonn, Bonn, Germany

Synopsis

While relaxation rate estimation substantially varies on the chosen fitting method, a tissue-specific T2 fitting scheme for the kidney is lacking. The current study aims to compare multiple T2 fitting methods, including square signal and mono-exponential with constant offsets, in high SNR and low SNR scenarios from identical data points. We compare standard deviations for fitting robustness and RMSE for the goodness of fit. Our finding suggests a mono-exponential with constant offsets is the most suitable method, for it yielded the lowest RMSE both in high and low SNR.

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