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Abstract #3289

Clinical DIADEM: Distortion-Free High-Resolution Diffusion-Weighted Imaging of the Brain.

Myung-Ho In1, Norbert G Campeau1, Joshua D Trzasko1, Daehun Kang1, Kirk M Welker1, John Huston III1, Yunhong Shu1, and Matt A Bernstein1
1Department of Radiology, Mayo Clinic, Rochester, MN, United States


Echo-planar based diffusion-weighted imaging (DWI) of the brain is prone to local image distortion which can lead to misdiagnosis or nondiagnostic image quality in areas prone to susceptibility effects. A novel distortion-free imaging scheme, termed DIADEM (Distortion-free Imaging: A Double Encoding Method) was recently introduced and optimized for brain imaging on a high-performance experimental Compact 3T system. In this study, we fully implement the DIADEM DWI technique on two 510-k cleared, whole-body 3T scanners and explore the clinical feasibility for its use in routine clinical practice.

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