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Abstract #3295

Characterization of the Zona incerta and Fields of Forel using QSM at 9.4T

Vinod Jangir Kumar1, Klaus Scheffler1,2, Gisela E Hagberg1,2, and Wolfgang Grodd1
1Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, 2Biomedical Magnetic Resonance, University Hospital and Eberhard-Karl’s University, Tuebingen, Germany


The subthalamic structures, like the zona incerta (ZI), fields of forel (FF), subthalamic nucleus (STN), and their surrounding structures, are poorly characterized regarding anatomical imaging. Using quantitative susceptibility mapping (QSM) at ultra-high-field, iron, and myelin mapping may allow an advanced characterization. Therefore, QSM data were acquired at 9.4 Tesla in 21 subjects to characterize the para- and diamagnetic properties of the ZI, FF, and their adjacent structures. In contrast to the FF, we found a higher contribution of diamagnetic and paramagnetic sources, i.e., iron, myelin, and calcium, in the STN and ZI.

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