Abstract #3328

Fast 3D fMRI Acquisition over a Small Field-of-View with (k, t)-Space Undersampling

Qingfei Luo¹, Kaibao Sun¹, Alessandro Scotti¹, Guangyu Dan^1,2, Muge Karaman^1,2, and Xiaohong Joe Zhou^1,2,3

¹Center for Magnetic Resonance Research, University of Illinois at Chicago, Chicago, IL, United States, ²Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL, United States, ³Departments of Radiology and Neurosurgery, University of Illinois at Chicago, Chicago, IL, United States

Synopsis

The simultaneous multi-slice EPI (SMS-EPI) technique is widely used in fast fMRI studies to achieve a short TR (e.g., < 1 s), but its image quality can be degraded when the slices span only a small brain area. In this study we develop a fast fMRI acquisition technique for imaging a small area by employing (k, t)-space undersampling and three-dimension reduced field-of-view imaging (k-t 3D-rFOVI). Our human fMRI experiments covering the visual cortex demonstrate that k-t 3D-rFOVI can provide higher detection sensitivity of brain activations than SMS-EPI.

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